YMC Hydrosphere C18

YMC Hydrosphere C18 Guard Columns

YMC recommends that you always use a guard column with the same packing material and of the recommended inner diameter for your column. A YMC guard column is normally composed of a cartridge holder and a guard cartridge. The holder can be used repeatedly. Guard cartridges should be changed frequently in order to maximise their protection of the main column.

    The separation of polar compounds in many cases requires highly aqueous mobile phase conditions to achieve sufficient retention on the stationary phase. Conventional reversed phase selectivities do not give reproducible results under these conditions mainly due to the collapse of the C18 chains. Hydrosphere C18 has been developed, on the ultra pure silica support of the ProFamily, to be stable in 100% aqueous eluents.

YMC Hydrosphere C18

Buy
Features
  • Stable under the use of 100% aqueous eluent
  • "Hydrophilic" C18 surface for enhanced polar recognition
  • No need for ion pair reagents
  • Based on highly inert, ultrapure, pH neutral silica
  • Specifically designed for pharmaceutical and biotechnology R&D
  • Large selection of guard dimensions available
Specifications
  Hydrosphere C18
Modification C18 (USP L1)
Particle size  3, 5 µm
Pore size  12 nm / 120 Å
Surface area 330 m2/g
Carbon load 12%
pH range 2 - 8
AQ stability 100% H2O eluents
Literature